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10.3402/jchimp.v6.32031

http://scihub22266oqcxt.onion/10.3402/jchimp.v6.32031
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suck abstract from ncbi


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pmid27609725      J+Community+Hosp+Intern+Med+Perspect 2016 ; 6 (4): ä
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  • Inappropriate use of commercial Antinuclear Antibody Testing in a community-based US hospital: a retrospective study #MMPMID27609725
  • Mohammed AS; Boddu P; Mael D; Samee M; Villines D
  • J Community Hosp Intern Med Perspect 2016[]; 6 (4): ä PMID27609725show ga
  • Healthcare providers use antinuclear antibodies (ANAs) to screen and diagnose patients with autoimmune diseases. In the recent years, commercial multiplex ANA kits have emerged as a convenient and fast diagnostic method. Diagnostic testing should follow sequenced algorithms: initial screen followed by specific antibody analysis. Second-level testing as an initial screen for autoimmune disease is inappropriate. We reviewed 68 patients with ANA comprehensive panels over a 6-month period from May 2015 to October 2015. We assessed appropriateness and estimated incurred losses from inappropriate testing. We found 92.6% (63 out of 68) of the ANA comprehensive panel results to be negative. Incurred losses from inappropriate ANA comprehensive panel testing were $66,000. Physicians should become familiar with ANA-sequenced diagnostic algorithms to avoid unnecessary higher level testing.
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