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Resolution of Otitis Media with Effusion in Children with Cleft Palate Followed Through 5 Years of Age #MMPMID27533493
Cleft Palate Craniofac J 2016[Sep]; 53 (5): 607-13 PMID27533493show ga
Objective: Describe the temporal pattern of otitis media with effusion (OME) resolution for a cohort of non-syndromic cleft palate children enrolled before palatoplasty and followed through 5 years of age. Design: Prospective, longitudinal study of the time course for OME resolution in infants and children with palatal clefts. Setting: Cleft Palate Craniofacial Center of a tertiary care pediatric hospital. Participants: Fifty-two children with cleft palate, 29 Male, 45 White, Veau 1?4 who had a Furlow-type palatoplasty between 10 and 24 months of age done by 1 of 6 surgeons. Interventions: Standard cleft palate management supplemented by study visits to the research clinic pre- and post-palatoplasty and then yearly to age 6 years for assessments of middle ear status by interval history, otoscopy and tympanometry. Main Outcome Measure: Age at otitis media resolution defined as the age in years at the first in a sequence of ?disease-free? diagnoses not interrupted or followed by any other diagnosis. Results: For ears/subjects, the cumulative percent OME resolution for ears/children at ages <1, 1, 2, 3, 4, 5 years was 4.1/4.4, 14.3/10.9, 31.6/21.7, 45.9/37.0, 56.1/50.0 and 70.4/60.9%. OME-resolution followed a simple linear time-curve with slopes of 13.5% (CI=12.2?14.8%, r2=0.99) and 11.9% (CI=10.1?13.6%, r2=0.99) resolutions per year for ears and children, respectively. Conclusions: There is a natural, age-related pattern of resolution for the persistent OME that affects most infants and young children with cleft palate that is not affected by palatoplasty.