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10.1016/j.cmet.2017.01.005 http://scihub22266oqcxt.onion/10.1016/j.cmet.2017.01.005 C5342930!5342930!28190773     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28190773.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cell+Metab 2017 ; 25 (3): 727-38 Nephropedia Template TP {{tp|p=28190773|t=2017. ? Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice |pdf=|usr=}}{{28190773}} gab.com Text Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice JO: Cell Metab http://www.kidney.de/pget.php?&tw=1&pmid=28190773 #FOAvip Type 1 diabetes (T1D) is a chronic autoimmune disease that involves immune-mediated destruction of ? cells. How ? cells respond to immune attack is unknown. We identified a population of ? cells during the progression of T1D in non-obese diabetic (NOD) mice that survives immune attack. This population develops from normal ? cells confronted with islet infiltrates. Pathways involving cell movement, growth and proliferation, immune responses, and cell death and survival are activated in these cells. There is reduced expression of ? cell identity genes and diabetes antigens and increased immune inhibitory markers and stemness genes. This new subpopulation is resistant to killing when diabetes is precipitated with cyclophosphamide. Human ? cells show similar changes when cultured with immune cells. These changes may account for the chronicity of the disease and the long-term survival of ? cells in some patients. Twit Text FOAVip Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice ????Cell Metab http://www.kidney.de/pget.php?&tw=1&pmid=28190773 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28190773 #FOAvip English Wikipedia <ref>{{Cite pmid|28190773}}</ref> ? Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice #MMPMID28190773 Rui J; Deng S; Arazi A; Perdigoto AL; Liu Z; Herold KC Cell Metab 2017[Mar]; 25 (3): 727-38 PMID28190773show ga Type 1 diabetes (T1D) is a chronic autoimmune disease that involves immune-mediated destruction of ? cells. How ? cells respond to immune attack is unknown. We identified a population of ? cells during the progression of T1D in non-obese diabetic (NOD) mice that survives immune attack. This population develops from normal ? cells confronted with islet infiltrates. Pathways involving cell movement, growth and proliferation, immune responses, and cell death and survival are activated in these cells. There is reduced expression of ? cell identity genes and diabetes antigens and increased immune inhibitory markers and stemness genes. This new subpopulation is resistant to killing when diabetes is precipitated with cyclophosphamide. Human ? cells show similar changes when cultured with immune cells. These changes may account for the chronicity of the disease and the long-term survival of ? cells in some patients. ä? Cells that Resist Immunological Attack Develop during Progression of(epmc).pdf DeepDyve Pubget Overpricing