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10.3390/ijms18020308 http://scihub22266oqcxt.onion/10.3390/ijms18020308 C5343844!5343844!28146134     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28146134&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28146134.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Mol+Sci 2017 ; 18 (2): ä Nephropedia Template TP {{tp|p=28146134|t=2017. Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification |pdf=|usr=}}{{28146134}} gab.com Text Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28146134 #FOAvip Next-generation sequencing (NGS) technology has expanded in the last decades with significant improvements in the reliability, sequencing chemistry, pipeline analyses, data interpretation and costs. Such advances make the use of NGS feasible in clinical practice today. This review describes the recent technological developments in NGS applied to the field of oncology. A number of clinical applications are reviewed, i.e., mutation detection in inherited cancer syndromes based on DNA-sequencing, detection of spliceogenic variants based on RNA-sequencing, DNA-sequencing to identify risk modifiers and application for pre-implantation genetic diagnosis, cancer somatic mutation analysis, pharmacogenetics and liquid biopsy. Conclusive remarks, clinical limitations, implications and ethical considerations that relate to the different applications are provided. Twit Text FOAVip Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28146134 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28146134 #FOAvip English Wikipedia <ref>{{Cite pmid|28146134}}</ref> Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification #MMPMID28146134 Kamps R; Brandão RD; van den Bosch BJ; Paulussen ADC; Xanthoulea S; Blok MJ; Romano A Int J Mol Sci 2017[Feb]; 18 (2): ä PMID28146134show ga Next-generation sequencing (NGS) technology has expanded in the last decades with significant improvements in the reliability, sequencing chemistry, pipeline analyses, data interpretation and costs. Such advances make the use of NGS feasible in clinical practice today. This review describes the recent technological developments in NGS applied to the field of oncology. A number of clinical applications are reviewed, i.e., mutation detection in inherited cancer syndromes based on DNA-sequencing, detection of spliceogenic variants based on RNA-sequencing, DNA-sequencing to identify risk modifiers and application for pre-implantation genetic diagnosis, cancer somatic mutation analysis, pharmacogenetics and liquid biopsy. Conclusive remarks, clinical limitations, implications and ethical considerations that relate to the different applications are provided. äNext-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Predic(epmc).pdf DeepDyve Pubget Overpricing