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Location, location, location Salmonella senses ethanolamine to gauge distinct host environments and coordinate gene expression |pdf=|usr=}}{{28357338}} gab.com Text Location, location, location Salmonella senses ethanolamine to gauge distinct host environments and coordinate gene expression JO: Microb Cell http://www.kidney.de/pget.php?&tw=1&pmid=28357338 #FOAvip Chemical and nutrient signaling mediate all cellular processes, ensuring survival in response to changing environmental conditions. Ethanolamine is a component of phosphatidylethanolamine, a major phospholipid of mammalian and bacterial cell membranes. Ethanolamine is abundant in the gastrointestinal (GI) tract from dietary sources as well as from the normal turnover of intestinal epithelial and bacterial cells in the gut. Additionally, mammalian cells maintain intracellular ethanolamine concentrations through low and high-affinity uptake systems and the internal recycling of phosphatidylethanolamine; therefore, ethanolamine is ubiquitous throughout the mammalian host. Although ethanolamine has profound signaling activity within mammalian cells by modulating inflammatory responses and intestinal physiology, ethanolamine is best appreciated as a nutrient for bacteria that supports growth. In our recent work (Anderson, et al. PLoS Pathog (2015), 11: e1005278), we demonstrated that Salmonella enterica serovar Typhimurium (Salmonella) exploits ethanolamine signaling to adapt to distinct host environments to precisely coordinate expression of genes encoding metabolism and virulence, which ultimately enhances disease progression. Twit Text FOAVip Location, location, location Salmonella senses ethanolamine to gauge distinct host environments and coordinate gene expression ????Microb Cell http://www.kidney.de/pget.php?&tw=1&pmid=28357338 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28357338 #FOAvip English Wikipedia <ref>{{Cite pmid|28357338}}</ref> Location, location, location Salmonella senses ethanolamine to gauge distinct host environments and coordinate gene expression #MMPMID28357338 Anderson CJ; Kendall MM Microb Cell ä[]; 3 (2): 89-91 PMID28357338show ga Chemical and nutrient signaling mediate all cellular processes, ensuring survival in response to changing environmental conditions. Ethanolamine is a component of phosphatidylethanolamine, a major phospholipid of mammalian and bacterial cell membranes. Ethanolamine is abundant in the gastrointestinal (GI) tract from dietary sources as well as from the normal turnover of intestinal epithelial and bacterial cells in the gut. Additionally, mammalian cells maintain intracellular ethanolamine concentrations through low and high-affinity uptake systems and the internal recycling of phosphatidylethanolamine; therefore, ethanolamine is ubiquitous throughout the mammalian host. Although ethanolamine has profound signaling activity within mammalian cells by modulating inflammatory responses and intestinal physiology, ethanolamine is best appreciated as a nutrient for bacteria that supports growth. In our recent work (Anderson, et al. PLoS Pathog (2015), 11: e1005278), we demonstrated that Salmonella enterica serovar Typhimurium (Salmonella) exploits ethanolamine signaling to adapt to distinct host environments to precisely coordinate expression of genes encoding metabolism and virulence, which ultimately enhances disease progression. äLocation, location, location Salmonella senses ethanolamine to gauge (epmc).pdf DeepDyve Pubget Overpricing