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10.3389/fmed.2017.00040 http://scihub22266oqcxt.onion/10.3389/fmed.2017.00040 C5387053!5387053!28443283     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28443283&cmd=llinks): Failed to open stream: HTTP request failed! 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Vascular Access Site for Renal Replacement Therapy in Acute Kidney Injury: A Post hoc Analysis of the ATN Study |pdf=|usr=}}{{28443283}} gab.com Text Vascular Access Site for Renal Replacement Therapy in Acute Kidney Injury: A Post hoc Analysis of the ATN Study JO: Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=28443283 #FOAvip Background: Acute kidney injury requiring renal replacement therapy (RRT) in the intensive care unit portends a poor prognosis. The decisions regarding dialysis catheter placement is based mainly on physician discretion with little evidence to support the choice of dialysis catheter location. Methods: The Veterans Affairs/National Institutes of Health Acute Renal Failure Trial Network Study was a multicenter, prospective, randomized trial of intensive vs. less intensive RRT in critically ill patients with AKI. We assessed the association of dialysis catheter location with dialysis catheter-related outcomes including catheter-related complications, mortality, dialysis dependence, and dialysis dose delivered. Results: Of the 1,124 patients enrolled in the ATN study, catheter data were available in 1,016 (90.39%) patients. A total of 91 (8.96%) subclavian, 387 (38.09%) internal jugular, and 538 (52.95%) femoral dialysis catheters were inserted. The femoral group was younger (58.39?�?16.27), had greater bleeding tendency [lower platelet count (96.00?�?109.35) with higher INR (2.01?�?2.19)], and had a higher baseline sequential organ failure assessment score on admission (14.59?�?3.61) compared to the other two groups. Dialysis catheter-related complications were low in this study with no significant difference in the rates of complications among all catheter locations. Mortality and dialysis dependence was lowest in the subclavian group, while the dose of dialysis delivered (Kt/V) remained lowest in the femoral group, after propensity score and center adjustments. Conclusion: Patient characteristics influence the choice of dialysis catheter location with a tendency to place femoral catheters in younger, sicker, and more coagulopathic patients. There were no statistically significant differences in complication rates among the three catheter locations, although femoral catheters may be associated with a lower delivered dose of dialysis during intermittent hemodialysis. Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT00076219. Twit Text FOAVip Vascular Access Site for Renal Replacement Therapy in Acute Kidney Injury: A Post hoc Analysis of the ATN Study ????Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=28443283 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28443283 #FOAvip English Wikipedia <ref>{{Cite pmid|28443283}}</ref> Vascular Access Site for Renal Replacement Therapy in Acute Kidney Injury: A Post hoc Analysis of the ATN Study #MMPMID28443283 Ng YH; Ganta K; Davis H; Pankratz VS; Unruh M Front Med (Lausanne) 2017[]; 4 (�): � PMID28443283show ga Background: Acute kidney injury requiring renal replacement therapy (RRT) in the intensive care unit portends a poor prognosis. The decisions regarding dialysis catheter placement is based mainly on physician discretion with little evidence to support the choice of dialysis catheter location. Methods: The Veterans Affairs/National Institutes of Health Acute Renal Failure Trial Network Study was a multicenter, prospective, randomized trial of intensive vs. less intensive RRT in critically ill patients with AKI. We assessed the association of dialysis catheter location with dialysis catheter-related outcomes including catheter-related complications, mortality, dialysis dependence, and dialysis dose delivered. Results: Of the 1,124 patients enrolled in the ATN study, catheter data were available in 1,016 (90.39%) patients. A total of 91 (8.96%) subclavian, 387 (38.09%) internal jugular, and 538 (52.95%) femoral dialysis catheters were inserted. The femoral group was younger (58.39?�?16.27), had greater bleeding tendency [lower platelet count (96.00?�?109.35) with higher INR (2.01?�?2.19)], and had a higher baseline sequential organ failure assessment score on admission (14.59?�?3.61) compared to the other two groups. Dialysis catheter-related complications were low in this study with no significant difference in the rates of complications among all catheter locations. Mortality and dialysis dependence was lowest in the subclavian group, while the dose of dialysis delivered (Kt/V) remained lowest in the femoral group, after propensity score and center adjustments. Conclusion: Patient characteristics influence the choice of dialysis catheter location with a tendency to place femoral catheters in younger, sicker, and more coagulopathic patients. There were no statistically significant differences in complication rates among the three catheter locations, although femoral catheters may be associated with a lower delivered dose of dialysis during intermittent hemodialysis. Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT00076219. �Vascular Access Site for Renal Replacement Therapy in Acute Kidney Inj(epmc).pdf DeepDyve Pubget Overpricing