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10.1109/JSSC.2014.2359219 http://scihub22266oqcxt.onion/10.1109/JSSC.2014.2359219 C5424881!5424881!28502989     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28502989&cmd=llinks): Failed to open stream: HTTP request failed! 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A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro |pdf=|usr=}}{{28502989}} gab.com Text A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro JO: IEEE J Solid-State Circuits http://www.kidney.de/pget.php?&tw=1&pmid=28502989 #FOAvip To advance our understanding of the functioning of neuronal ensembles, systems are needed to enable simultaneous recording from a large number of individual neurons at high spatiotemporal resolution and good signal-to-noise ratio. Moreover, stimulation capability is highly desirable for investigating, for example, plasticity and learning processes. Here, we present a microelectrode array (MEA) system on a single CMOS die for in vitro recording and stimulation. The system incorporates 26,400 platinum electrodes, fabricated by in-house post-processing, over a large sensing area (3.85 × 2.10 mm2) with sub-cellular spatial resolution (pitch of 17.5 ?m). Owing to an area and power efficient implementation, we were able to integrate 1024 readout channels on chip to record extracellular signals from a user-specified selection of electrodes. These channels feature noise values of 2.4 ?Vrms in the action-potential band (300 Hz?10 kHz) and 5.4 ?Vrms in the local-field-potential band (1 Hz?300 Hz), and provide programmable gain (up to 78 dB) to accommodate various biological preparations. Amplified and filtered signals are digitized by 10 bit parallel single-slope ADCs at 20 kSamples/s. The system also includes 32 stimulation units, which can elicit neural spikes through either current or voltage pulses. The chip consumes only 75 mW in total, which obviates the need of active cooling even for sensitive cell cultures. Twit Text FOAVip A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro ????IEEE J Solid-State Circuits http://www.kidney.de/pget.php?&tw=1&pmid=28502989 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28502989 #FOAvip English Wikipedia <ref>{{Cite pmid|28502989}}</ref> A 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Recording and Stimulation of Electrogenic Cells In Vitro #MMPMID28502989 Ballini M; Müller J; Livi P; Chen Y; Frey U; Stettler A; Shadmani A; Viswam V; Jones IL; Jäckel D; Radivojevic M; Lewandowska MK; Gong W; Fiscella M; Bakkum DJ; Heer F; Hierlemann A IEEE J Solid-State Circuits 2014[Nov]; 49 (11): 2705-19 PMID28502989show ga To advance our understanding of the functioning of neuronal ensembles, systems are needed to enable simultaneous recording from a large number of individual neurons at high spatiotemporal resolution and good signal-to-noise ratio. Moreover, stimulation capability is highly desirable for investigating, for example, plasticity and learning processes. Here, we present a microelectrode array (MEA) system on a single CMOS die for in vitro recording and stimulation. The system incorporates 26,400 platinum electrodes, fabricated by in-house post-processing, over a large sensing area (3.85 × 2.10 mm2) with sub-cellular spatial resolution (pitch of 17.5 ?m). Owing to an area and power efficient implementation, we were able to integrate 1024 readout channels on chip to record extracellular signals from a user-specified selection of electrodes. These channels feature noise values of 2.4 ?Vrms in the action-potential band (300 Hz?10 kHz) and 5.4 ?Vrms in the local-field-potential band (1 Hz?300 Hz), and provide programmable gain (up to 78 dB) to accommodate various biological preparations. Amplified and filtered signals are digitized by 10 bit parallel single-slope ADCs at 20 kSamples/s. The system also includes 32 stimulation units, which can elicit neural spikes through either current or voltage pulses. The chip consumes only 75 mW in total, which obviates the need of active cooling even for sensitive cell cultures. äA 1024-Channel CMOS Microelectrode Array With 26,400 Electrodes for Re(epmc).pdf DeepDyve Pubget Overpricing