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10.1098/rsta.2016.0289 http://scihub22266oqcxt.onion/10.1098/rsta.2016.0289 C5434080!5434080!28507234     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28507234&cmd=llinks): Failed to open stream: HTTP request failed! 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Modelling far field pacing for terminating spiral waves pinned to ischaemic heterogeneities in cardiac tissue |pdf=|usr=}}{{28507234}} gab.com Text Modelling far field pacing for terminating spiral waves pinned to ischaemic heterogeneities in cardiac tissue JO: Philos Trans A Math Phys Eng Sci http://www.kidney.de/pget.php?&tw=1&pmid=28507234 #FOAvip In cardiac tissue, electrical spiral waves pinned to a heterogeneity can be unpinned (and eventually terminated) using electric far field pulses and recruiting the heterogeneity as a virtual electrode. While for isotropic media the process of unpinning is much better understood, the case of an anisotropic substrate with different conductivities in different directions still needs intensive investigation. To study the impact of anisotropy on the unpinning process, we present numerical simulations based on the bidomain formulation of the phase I of the Luo and Rudy action potential model modified due to the occurrence of acute myocardial ischaemia. Simulating a rotating spiral wave pinned to an ischaemic heterogeneity, we compare the success of sequences of far field pulses in the isotropic and the anisotropic case for spirals still in transient or in steady rotation states. Our results clearly indicate that the range of pacing parameters resulting in successful termination of pinned spiral waves is larger in anisotropic tissue than in an isotropic medium.This article is part of the themed issue ?Mathematical methods in medicine: neuroscience, cardiology and pathology?. Twit Text FOAVip Modelling far field pacing for terminating spiral waves pinned to ischaemic heterogeneities in cardiac tissue ????Philos Trans A Math Phys Eng Sci http://www.kidney.de/pget.php?&tw=1&pmid=28507234 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28507234 #FOAvip English Wikipedia <ref>{{Cite pmid|28507234}}</ref> Modelling far field pacing for terminating spiral waves pinned to ischaemic heterogeneities in cardiac tissue #MMPMID28507234 Boccia E; Luther S; Parlitz U Philos Trans A Math Phys Eng Sci 2017[Jun]; 375 (2096): ä PMID28507234show ga In cardiac tissue, electrical spiral waves pinned to a heterogeneity can be unpinned (and eventually terminated) using electric far field pulses and recruiting the heterogeneity as a virtual electrode. While for isotropic media the process of unpinning is much better understood, the case of an anisotropic substrate with different conductivities in different directions still needs intensive investigation. To study the impact of anisotropy on the unpinning process, we present numerical simulations based on the bidomain formulation of the phase I of the Luo and Rudy action potential model modified due to the occurrence of acute myocardial ischaemia. Simulating a rotating spiral wave pinned to an ischaemic heterogeneity, we compare the success of sequences of far field pulses in the isotropic and the anisotropic case for spirals still in transient or in steady rotation states. Our results clearly indicate that the range of pacing parameters resulting in successful termination of pinned spiral waves is larger in anisotropic tissue than in an isotropic medium.This article is part of the themed issue ?Mathematical methods in medicine: neuroscience, cardiology and pathology?. äModelling far field pacing for terminating spiral waves pinned to isch(epmc).pdf DeepDyve Pubget Overpricing