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10.18632/oncotarget.16107 http://scihub22266oqcxt.onion/10.18632/oncotarget.16107 C5458202!5458202!28415720     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28415720&cmd=llinks): Failed to open stream: HTTP request failed! 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The function of oxytocin: a potential biomarker for prostate cancer diagnosis and promoter of prostate cancer |pdf=|usr=}}{{28415720}} gab.com Text The function of oxytocin: a potential biomarker for prostate cancer diagnosis and promoter of prostate cancer JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28415720 #FOAvip Purpose: To measure the level of oxytocin in serum and prostate cancer (PCa) tissue and study its effect on the proliferation of PCa cells. Results: Oxytocin level in serum was significantly increased in PCa patients compared with the no-carcinoma individuals. Additionally, the levels of oxytocin and its receptor were also elevated in the PCa tissue. However, no significant difference existed among the PCa of various Gleason grades. Western blot analysis confirmed the previous results and revealed an increased expression level of APPL1. Materials and methods: The level of oxytocin in serum was measured by ELISA analysis. The expression of oxytocin and its receptor in prostate was analyzed by immunohistochemistry. The proliferation and apoptosis of PCa cells were assessed by the Cell Counting Kit 8 (CCK8) assay, cell cycle analysis and caspase3 activity analysis, respectively. Western blot analysis was used for the detection of PCNA, Caspase3 and APPL1 protein levels. Conclusions: Serum and prostatic oxytocin levels are increased in the PCa subjects. Serum oxytocin level may be a biomarker for PCa in the future. Oxytocin increases PCa growth and APPL1 expression. Twit Text FOAVip The function of oxytocin: a potential biomarker for prostate cancer diagnosis and promoter of prostate cancer ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28415720 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28415720 #FOAvip English Wikipedia <ref>{{Cite pmid|28415720}}</ref> The function of oxytocin: a potential biomarker for prostate cancer diagnosis and promoter of prostate cancer #MMPMID28415720 Xu H; Fu S; Chen Q; Gu M; Zhou J; Liu C; Chen Y; Wang Z Oncotarget 2017[May]; 8 (19): 31215-26 PMID28415720show ga Purpose: To measure the level of oxytocin in serum and prostate cancer (PCa) tissue and study its effect on the proliferation of PCa cells. Results: Oxytocin level in serum was significantly increased in PCa patients compared with the no-carcinoma individuals. Additionally, the levels of oxytocin and its receptor were also elevated in the PCa tissue. However, no significant difference existed among the PCa of various Gleason grades. Western blot analysis confirmed the previous results and revealed an increased expression level of APPL1. Materials and methods: The level of oxytocin in serum was measured by ELISA analysis. The expression of oxytocin and its receptor in prostate was analyzed by immunohistochemistry. The proliferation and apoptosis of PCa cells were assessed by the Cell Counting Kit 8 (CCK8) assay, cell cycle analysis and caspase3 activity analysis, respectively. Western blot analysis was used for the detection of PCNA, Caspase3 and APPL1 protein levels. Conclusions: Serum and prostatic oxytocin levels are increased in the PCa subjects. Serum oxytocin level may be a biomarker for PCa in the future. Oxytocin increases PCa growth and APPL1 expression. äThe function of oxytocin: a potential biomarker for prostate cancer di(epmc).pdf DeepDyve Pubget Overpricing