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10.1016/j.cancergen.2016.03.004 http://scihub22266oqcxt.onion/10.1016/j.cancergen.2016.03.004 C5497490!5497490!27132463     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27132463&cmd=llinks): Failed to open stream: HTTP request failed! 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Current State of Pediatric Sarcoma Biology and Opportunities for Future Discovery: A Report from the Sarcoma Translational Research Workshop |pdf=|usr=}}{{27132463}} gab.com Text Current State of Pediatric Sarcoma Biology and Opportunities for Future Discovery: A Report from the Sarcoma Translational Research Workshop JO: Cancer Genet http://www.kidney.de/pget.php?&tw=1&pmid=27132463 #FOAvip Sarcomas are a rare subgroup of pediatric cancers comprised of a variety of bone and soft-tissue tumors. While significant advances have been made in improving outcomes of patients with localized pediatric sarcomas since the addition of systemic chemotherapy to local control many decades ago, outcomes for patients with metastatic and relapsed sarcoma remain poor with few novel therapeutics identified to date. With the advent of new technologies to study cancer genomes, transcriptomes and epigenomes, our understanding of sarcoma biology has improved tremendously in a relatively short period of time. However, much remains to be accomplished in this arena especially with regard to translating all of this new knowledge to the bedside. To this end, a meeting was convened in Philadelphia, PA on April 18, 2015 sponsored by the QuadW foundation, Children?s Oncology Group and CureSearch for Children?s Cancer that brought together sarcoma clinicians and scientists from North America to review the current state of pediatric sarcoma biology and ongoing/planned genomics based clinical trials in an effort to identify and bridge knowledge gaps that continue to exist at the current time. At the conclusion of the workshop, three key objectives that would significantly further our understanding of sarcoma were identified and a proposal was put forward to develop an all-encompassing pediatric sarcoma biology protocol that would address these specific needs. This review summarizes the proceedings of the workshop. Twit Text FOAVip Current State of Pediatric Sarcoma Biology and Opportunities for Future Discovery: A Report from the Sarcoma Translational Research Workshop ????Cancer Genet http://www.kidney.de/pget.php?&tw=1&pmid=27132463 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27132463 #FOAvip English Wikipedia <ref>{{Cite pmid|27132463}}</ref> Current State of Pediatric Sarcoma Biology and Opportunities for Future Discovery: A Report from the Sarcoma Translational Research Workshop #MMPMID27132463 Hingorani P; Janeway K; Crompton BD; Kadoch C; Mackall CL; Khan J; Shern JF; Schiffman J; Mirabello L; Savage SA; Ladanyi M; Meltzer P; Bult CJ; Adamson PC; Lupo PJ; Mody R; DuBois SG; Parsons DW; Khanna C; Lau C; Hawkins DS; Randall RL; Smith M; Sorensen PH; Plon SE; Skapek SX; Lessnick S; Gorlick R; Reed DR Cancer Genet 2016[May]; 209 (5): 182-94 PMID27132463show ga Sarcomas are a rare subgroup of pediatric cancers comprised of a variety of bone and soft-tissue tumors. While significant advances have been made in improving outcomes of patients with localized pediatric sarcomas since the addition of systemic chemotherapy to local control many decades ago, outcomes for patients with metastatic and relapsed sarcoma remain poor with few novel therapeutics identified to date. With the advent of new technologies to study cancer genomes, transcriptomes and epigenomes, our understanding of sarcoma biology has improved tremendously in a relatively short period of time. However, much remains to be accomplished in this arena especially with regard to translating all of this new knowledge to the bedside. To this end, a meeting was convened in Philadelphia, PA on April 18, 2015 sponsored by the QuadW foundation, Children?s Oncology Group and CureSearch for Children?s Cancer that brought together sarcoma clinicians and scientists from North America to review the current state of pediatric sarcoma biology and ongoing/planned genomics based clinical trials in an effort to identify and bridge knowledge gaps that continue to exist at the current time. At the conclusion of the workshop, three key objectives that would significantly further our understanding of sarcoma were identified and a proposal was put forward to develop an all-encompassing pediatric sarcoma biology protocol that would address these specific needs. This review summarizes the proceedings of the workshop. äCurrent State of Pediatric Sarcoma Biology and Opportunities for Futur(epmc).pdf DeepDyve Pubget Overpricing