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10.1155/2017/7919201 http://scihub22266oqcxt.onion/10.1155/2017/7919201 C5511641!5511641!28752097     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28752097&cmd=llinks): Failed to open stream: HTTP request failed! 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Efficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Degeneration: A Meta-Analysis of Animal Studies |pdf=|usr=}}{{28752097}} gab.com Text Efficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Degeneration: A Meta-Analysis of Animal Studies JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=28752097 #FOAvip Objectives: Several animal studies have demonstrated the positive effects of platelet-rich plasma (PRP) on disc degeneration retardation. The present meta-analysis was to verify the efficacy of PRP in retarding disc degeneration in animal. Methods: Relevant studies were identified and evaluated according to our inclusion and exclusion criteria. The standardized mean difference (SMD) and related 95% confidence interval (95% CI) were estimated to assess PRP efficiency. Results: In total, eleven studies were included in this meta-analysis. Significant differences were found in the PRP treatment group, which showed increased disc height (SMD = 2.66, 95% CI: 1.86, 3.47, p = 0.000), increased MRI T2 signal intensity (SMD = ?3.29, 95% CI: ?4.44, ?2.13, p = 0.000), and decreased histological degeneration grade (SMD = ?4.28, 95% CI: ?5.26, ?3.30, p = 0.000). However, no significant increase in collagen II expression was found (SMD = 25389.74, 95% CI: ?27585.72, 78365.21, p = 0.348). Apart from the subgroup analysis of the disc height based on animal species (pig) and disc degeneration model (chymopapain induction), other subgroup analysis based on animal species (rabbit and rat), study design, disc degeneration model, and follow-up period demonstrated that PRP treatment can significantly restore disc height and increase MRI T2 signal intensity. Conclusions: PRP treatment is potentially effective in restoring disc height of rodent rabbit and rat, reducing histological degeneration grade, and increasing MRI T2 image signal. PRP injection may be promising therapy for retarding disc degeneration. Twit Text FOAVip Efficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Degeneration: A Meta-Analysis of Animal Studies ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=28752097 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28752097 #FOAvip English Wikipedia <ref>{{Cite pmid|28752097}}</ref> Efficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Degeneration: A Meta-Analysis of Animal Studies #MMPMID28752097 Li P; Zhang R; Zhou Q Biomed Res Int 2017[]; 2017 (ä): ä PMID28752097show ga Objectives: Several animal studies have demonstrated the positive effects of platelet-rich plasma (PRP) on disc degeneration retardation. The present meta-analysis was to verify the efficacy of PRP in retarding disc degeneration in animal. Methods: Relevant studies were identified and evaluated according to our inclusion and exclusion criteria. The standardized mean difference (SMD) and related 95% confidence interval (95% CI) were estimated to assess PRP efficiency. Results: In total, eleven studies were included in this meta-analysis. Significant differences were found in the PRP treatment group, which showed increased disc height (SMD = 2.66, 95% CI: 1.86, 3.47, p = 0.000), increased MRI T2 signal intensity (SMD = ?3.29, 95% CI: ?4.44, ?2.13, p = 0.000), and decreased histological degeneration grade (SMD = ?4.28, 95% CI: ?5.26, ?3.30, p = 0.000). However, no significant increase in collagen II expression was found (SMD = 25389.74, 95% CI: ?27585.72, 78365.21, p = 0.348). Apart from the subgroup analysis of the disc height based on animal species (pig) and disc degeneration model (chymopapain induction), other subgroup analysis based on animal species (rabbit and rat), study design, disc degeneration model, and follow-up period demonstrated that PRP treatment can significantly restore disc height and increase MRI T2 signal intensity. Conclusions: PRP treatment is potentially effective in restoring disc height of rodent rabbit and rat, reducing histological degeneration grade, and increasing MRI T2 image signal. PRP injection may be promising therapy for retarding disc degeneration. äEfficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Dege(epmc).pdf DeepDyve Pubget Overpricing