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10.1159/000358221 http://scihub22266oqcxt.onion/10.1159/000358221 C5586872!5586872!24504150     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24504150&cmd=llinks): Failed to open stream: HTTP request failed! 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Switch-Associated Protein 70 Antibodies in Multiple Sclerosis: Possible Association with Disease Progression |pdf=|usr=}}{{24504150}} gab.com Text Switch-Associated Protein 70 Antibodies in Multiple Sclerosis: Possible Association with Disease Progression JO: Med Princ Pract http://www.kidney.de/pget.php?&tw=1&pmid=24504150 #FOAvip Objective: This study was conducted to identify a biomarker for multiple sclerosis (MS) that can be used as a predictor of relapse and disability. Materials and Methods: Sera of 26 consecutive relapsing-remitting MS (RRMS) patients were screened for switch-associated protein 70 (SWAP-70) antibody, which was previously identified by protein macroarray. The serum levels of several cytokines, chemokines and soluble adhesion molecules related to MS attacks were measured by enzyme-linked immunosorbent assay (ELISA). A possible correlation was sought among levels of SWAP-70 antibody, measured humoral factors and disability scores. Results: ELISA studies showed high-titre SWAP-70 antibodies in 16 (61.5%) RRMS sera obtained during the attack period and 9 (34.6%) sera obtained during remission. There was a significant inverse correlation between SWAP-70 antibody levels and expanded disability status scale scores, CXCL10, soluble VCAM-1, CXCL13 and soluble VLA-4 levels. Conclusion: Our results showed that SWAP-70 antibodies could potentially be utilized as relapse and prognostic biomarkers in MS. Whether or not SWAP-70 antibodies have any effect on disease mechanisms requires further investigation. Twit Text FOAVip Switch-Associated Protein 70 Antibodies in Multiple Sclerosis: Possible Association with Disease Progression ????Med Princ Pract http://www.kidney.de/pget.php?&tw=1&pmid=24504150 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24504150 #FOAvip English Wikipedia <ref>{{Cite pmid|24504150}}</ref> Switch-Associated Protein 70 Antibodies in Multiple Sclerosis: Possible Association with Disease Progression #MMPMID24504150 T�rko?lu R; Gencer M; Ekmek�i D; Ulusoy C; Erda? E; ?ehito?lu E; �avu? F; Haytural H; K���kerden M; Yal�?nkaya N; Turan S; Akba?-Demir D; �oban A; Vural B; T�z�n E Med Princ Pract 2014[May]; 23 (3): 239-45 PMID24504150show ga Objective: This study was conducted to identify a biomarker for multiple sclerosis (MS) that can be used as a predictor of relapse and disability. Materials and Methods: Sera of 26 consecutive relapsing-remitting MS (RRMS) patients were screened for switch-associated protein 70 (SWAP-70) antibody, which was previously identified by protein macroarray. The serum levels of several cytokines, chemokines and soluble adhesion molecules related to MS attacks were measured by enzyme-linked immunosorbent assay (ELISA). A possible correlation was sought among levels of SWAP-70 antibody, measured humoral factors and disability scores. Results: ELISA studies showed high-titre SWAP-70 antibodies in 16 (61.5%) RRMS sera obtained during the attack period and 9 (34.6%) sera obtained during remission. There was a significant inverse correlation between SWAP-70 antibody levels and expanded disability status scale scores, CXCL10, soluble VCAM-1, CXCL13 and soluble VLA-4 levels. Conclusion: Our results showed that SWAP-70 antibodies could potentially be utilized as relapse and prognostic biomarkers in MS. Whether or not SWAP-70 antibodies have any effect on disease mechanisms requires further investigation. �Switch-Associated Protein 70 Antibodies in Multiple Sclerosis: Possibl(epmc).pdf DeepDyve Pubget Overpricing