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10.1177/1740774517725697 http://scihub22266oqcxt.onion/10.1177/1740774517725697 C5700799!5700799!28830236     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28830236.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Clin+Trials 2017 ; 14 (5): 451-61 Nephropedia Template TP {{tp|p=28830236|t=2017. Testing many treatments within a single protocol over 10 years at MRC CTU at UCL: Multi-arm, multi stage platform, umbrella and basket protocols |pdf=|usr=}}{{28830236}} gab.com Text Testing many treatments within a single protocol over 10 years at MRC CTU at UCL: Multi-arm, multi stage platform, umbrella and basket protocols JO: Clin Trials http://www.kidney.de/pget.php?&tw=1&pmid=28830236 #FOAvip There is real need to change how we do some of our clinical trials, as currently the testing and development process is too slow, too costly and too failure-prone - often we find that a new treatment is no better than the current standard. Much of the focus on the development and testing pathway has been in improving the design of phase I and II trials. In this paper we present examples of new methods for improving the design of phase III trials (and the necessary lead up to them) as they are the most time consuming and expensive part of the pathway. Key to all these methods is the aim to test many treatments and/or pose many therapeutic questions within one protocol. Twit Text FOAVip Testing many treatments within a single protocol over 10 years at MRC CTU at UCL: Multi-arm, multi stage platform, umbrella and basket protocols ????Clin Trials http://www.kidney.de/pget.php?&tw=1&pmid=28830236 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28830236 #FOAvip English Wikipedia <ref>{{Cite pmid|28830236}}</ref> Testing many treatments within a single protocol over 10 years at MRC CTU at UCL: Multi-arm, multi stage platform, umbrella and basket protocols #MMPMID28830236 Parmar MK; Sydes MR; Cafferty FH; Choodari-Oskooei B; Langley RE; Brown L; Phillips PP; Spears MR; Rowley S; Kaplan R; James ND; Maughan T; Paton N; Royston PJ Clin Trials 2017[Oct]; 14 (5): 451-61 PMID28830236show ga There is real need to change how we do some of our clinical trials, as currently the testing and development process is too slow, too costly and too failure-prone - often we find that a new treatment is no better than the current standard. Much of the focus on the development and testing pathway has been in improving the design of phase I and II trials. In this paper we present examples of new methods for improving the design of phase III trials (and the necessary lead up to them) as they are the most time consuming and expensive part of the pathway. Key to all these methods is the aim to test many treatments and/or pose many therapeutic questions within one protocol. äTesting many treatments within a single protocol over 10 years at MRC (epmc).pdf DeepDyve Pubget Overpricing