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Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology #MMPMID29699478
Pereira H; Caldeira D; Teles RC; Costa M; da Silva PC; da Gama Ribeiro V; Brandão V; Martins D; Matias F; Pereira-Machado F; Baptista J; Abreu PFe; Santos R; Drummond A; de Carvalho HC; Calisto J; Silva JC; Pipa JL; Marques J; Sousa P; Fernandes R; Ferreira RC; Ramos S; Oliveira EI; de Sousa Almeida M
BMC Cardiovasc Disord 2018[]; 18 (ä): ä PMID29699478show ga
Background: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in ?real-world? settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006?2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54?1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35?0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.